1. The first settlers in Pike County arrived in 1818. 2. The first county seat was established in 1821 at Louisiana, Missouri. 3. The first courthouse was built in 1822. 4. The first school in the county was established in 1825. 5. The first newspaper, the Pike County Republican, was published in 1837. 6. The first railroad line was built in 1855. 7. The first bridge across the Mississippi Rive...
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