McDonough County is located in west-central Illinois and is part of the Macomb-Western Illinois Metropolitan Statistical Area. The county seat is Macomb.

McDonough County is governed by a board of commissioners, which is composed of seven members elected from seven districts. The county is also served by a state's attorney, sheriff, coroner, and circuit court clerk.

McDonough County is home to Western Illinois University, a public university located in Macomb. The county is also home to Spoon River College, a community college located in Canton.

McDonough County is part of the Macomb, IL Micropolitan Statistical Area, which is also included in the Peoria-Canton, IL Combined Statistical Area. The county is also part of the Great River Economic Development District.

For the most up-to-date and in-depth information, please check the public records links below.